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Biography
Donmez is an experienced researcher in the field of cancer research. He possesses expertise in molecular mechanisms, primarily aiming to enhance the understanding of cancer development mechanisms through his work. To achieve this objective, he collaborates with scientists across various universities.
Academically, he completed his Ph.D. in Cancer Sciences at The University of Manchester (2020-2024). His prior education includes a Master's degree in Medical Genetics from Selçuk University Faculty of Medicine (2011-2014) and a Bachelor's degree in Biology from Selçuk University Faculty of Science (2007-2011).
His technical proficiencies encompass DNA/RNA-based analyses (primer design, Classic PCR, qPCR, RFLP, CRISPR) , protein-based analyses (Western Blot, Immunofluorescence, Enzyme-Linked Immunosorbent Assay) , in-vitro analyses (MTT, SRB, colorimetric analyses, transfection techniques, morphology analyses, Flow cytometry, invasion/migration analyses, Seahorse analysis, clonogenic analyses) , and cytogenetic-based analyses (Karyotyping, FISH).
Research projects constitute a significant part of his career. His Ph.D. project involved investigating the role of MCT1 in endometrial cancer. He has also examined the effects of medicarpin on head and neck cancer cell lines and researched the autophagic effects of melatonin on breast cancer stem cells. Furthermore, he participated in projects focusing on the apoptotic and differentiation effects of melatonin on breast cancer stem cells (TUBITAK 1002) and the investigation of microRNA expression profiles related to pregnancy in mare endometrium (TUBITAK 1001).
Education
2020 - 2025
2020 - 2025Doctorate
The University of Manchester, England
2011 - 2014
2011 - 2014Postgraduate
Selcuk University, Turkey
2007 - 2011
2007 - 2011Undergraduate
Selcuk University, Turkey
Dissertations
2025
2025Doctorate
Investigating the role of MCT1 in endometrial cancer
The University of Manchester, Cancer Research
2014
2014Postgraduate
Melatoninin meme kanseri kök hücrelerindeki otofajik etkisininin incelenmesi
Selcuk University, Tıp Fakültesi / Sağlık Bilimleri
Certificates, Courses and Trainings
2026
2026Scopus Organization Profile Analysis Webinar
Other
Elsevier
2026
2026Scopus Basic Training for Researchers
Other
Elsevier
2026
2026Probleme Dayalı Öğrenme (PDÖ)
Education Management and Planning
Sivas Cumhuriyet University
2025
2025Eğiticilerin Eğitimi
Education Management and Planning
Sivas Cumhuriyet University
2020
2020Compressed Gases Safety
Occupational Health and Safety
PGS Training
2009
2009Etkili Yönetim ve Liderlik Becerileri
Entrepreneurship
KOSGEB
2009
2009Yönetim Programları
Entrepreneurship
KOSGEB
2009
2009İletişim ve Beden Dili
Personal Evolution
KOSGEB
Research Areas
Medicine
Molecular Biology and Genetics
Fundamental Medical Sciences
Research Areas Based on Academic Activities
Avesis Research Areas
WoS Research Areas
Scopus Research Areas
Academic Positions
2025 - Present
2025 - PresentSivas Cumhuriyet University, Tıp Fakültesi
Articles
2025
20251. Ketoprofen Pharmacokinetics in Goats Following Repeated Treatment Alone or in Combination With Cefquinome
Corum D. D., Corum O., Giorgi M., Kartal Ş., Türk E., Sakın F., et al.
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS
, vol.26, no.12, pp.1-7, 2025 (SCI-Expanded, Scopus)
2025
20252. Exploration of Small Non-Coding RNAs as Molecular Markers of Ram Sperm Fertility
Bodu M., Hitit M., Donmez H., Kaya A., Ugur M. R., Memili E.
International journal of molecular sciences
, vol.26, no.6, 2025 (SCI-Expanded, Scopus)
2022
20223. The effect of medicarpin on PTEN/AKT signal pathway in head and neck squamous cell carcinoma
Kalaycı A., Donmez H., Hitit M., Seven S., Eser N., Kurar E., et al.
Journal of Cancer Research and Therapeutics
, vol.18, no.1, pp.180-184, 2022 (SCI-Expanded, Scopus)
2018
20184. Investigation of Leptin Receptor and eNOS Gene Polymorphisms in Preeclamptic Umbilical Cords
Seçer Çelik F., Dönmez H., Çelen Kaya E., Büyük E., Vural H.
World Journal of Gynecology & Women’s Health
, vol.1, no.3, 2018 (Peer-Reviewed Journal)
2018
20185. Effects of melatonin on apoptosis and cell differentiation in MCF-7 derived cancer stem cells
Dönmez H.
Cellular and Molecular Biology
, vol.64, no.12, pp.56-61, 2018 (SCI-Expanded)
2018
20186. A cardioprotective role of Nerium oleander with the expression of hypoxia inducible factor 2A mRNA by increasing antioxidant enzymes in rat heart tissue
Hitit M., ÇORUM O., DURNA ÇORUM D., Donmez H., ÇETİN G., Dik B., et al.
Acta Scientiae Veterinariae
, vol.46, no.1, 2018 (SCI-Expanded, Scopus)
2017
20177. Investigation of autophagic effects of melatonin on breast cancer stem cells
Donmez H., Kocak N., Yildirim I. H.
Biomedical Research (India)
, vol.28, no.11, pp.5048-5053, 2017 (Scopus)
2017
20178. Alcoholic extract of tarantula cubensis induces apoptosis in MCF-7 cell line
Ayse E., Çorum O., Durna Çorum D., Hitit M., Donmez H., Guzeloglu A.
Biomedical Research (India)
, vol.28, no.8, pp.3660-3665, 2017 (Scopus)
2016
20169. Tunicamycin-induced endoplasmic reticulum stress reduces in vitro subpopulation and invasion of CD44+/CD24- phenotype breast cancer stem cells
Nami B., Donmez H., Kocak N.
Experimental and Toxicologic Pathology
, vol.68, no.7, pp.419-426, 2016 (SCI-Expanded, Scopus)
2015
201510. Autophagy reduces subpopulation of CD44+/CD24/low phenotype cancer stem cells in MCF7 and Hep-2 cells culture
Nami B., Dönmez H., Koçak N.
Journal of Cancer Stem Cell Research
, vol.3, 2015 (Peer-Reviewed Journal)
Papers Presented at Peer-Reviewed Scientific Conferences
2023
20231. Exploring the role of MCT1 in metabolic adaptation in endometrial cancer cell lines
DÖNMEZ H.
BACR trailblazers in cancer research, 22 - 23 June 2023, (Summary Text)
2018
20182. Cardioprotective Role of Nerium oleander with the Expression of Hypoxia Inducible Factor 2A mRNA by Increasing Antioxidant Enzymes in Rat Heart Tissue
HİTİT M., ÇORUM O., DURNA ÇORUM D., DÖNMEZ H., KURAR E.
International Congress on Engineering and Life Science, 26 - 29 April 2018, (Summary Text)
2018
20183. Investigation of the Effect of Medicarpin on Head and Neck Cancer Cell Line
KALAYCI A., DÖNMEZ H., HİTİT M., KURAR E.
7th International Molecular Biology and Biotechnology Congress, 25 - 27 April 2018, (Summary Text)
2018
20184. Effects of acrylamide on oxidative stress modulators in HEK293 cell line
SEÇER ÇELİK F., KALAYCI A., DÖNMEZ H.
7th International Molecular Biology and Biotechnology Congress, 25 - 27 April 2018, (Summary Text)
2018
20185. Selection of Reliable Reference Genes for qPCR Analysis on MCF7 Cells with Melatonin treated.
DÖNMEZ H., KOÇAK N., HİTİT M., KALAYCI A., SEÇER ÇELİK F., KURAR E.
7th International Molecular Biology and Biotechnology Congress, 25 - 27 April 2018, (Summary Text)
2018
20186. Selection of Reliable Reference Genes for qRT-PCR Analysis of Medicarpin-treated HNSCC Cells
DÖNMEZ H., KALAYCI A., HİTİT M., EROĞLU GÜNEŞ C., KURAR E.
International Congress on Engineering and Life Science, 26 April 2018, (Summary Text)
2018
20187. Investigation of Gene Polymorphisms Associated with Vasodilator Effect of Leptin in in-vitro Pre-eclampsia Model
SEÇER ÇELİK F., DÖNMEZ H., VURAL H.
7th International Molecular Biology and Biotechnology Congress, 25 April 2018, (Summary Text)
2017
20178. Transcriptional Regulation of Hypoxia Inducible Factors (HIF1α, HIF2α, HIF3α) by Nerium Oleander Distillate in Rat Testis
HİTİT M., ÇORUM O., DURNA ÇORUM D., DÖNMEZ H., ER A.
V International KOP Regional Development Symposium, 26 - 28 October 2017, (Summary Text)
2016
20169. Investigation of the Effect of Melatonin Cell Viability and Apoptosis in HNSCC
KALAYCI A., DÖNMEZ H.
6th Multidisciplinary Cancer Research Congress, 27 - 30 October 2016, (Summary Text)
2016
201610. Investigation of the Autophagic Effects of Melatonin on Breast Cancer Stem Cells
DÖNMEZ H., KOÇAK N.
5th International Molecular Biology and Biotechnology Congress, 25 - 29 August 2016, (Summary Text)
2015
201511. Tarantula cubensis extract may inhibit breast cancer cells viability
ER A., ÇORUM O., DURNA ÇORUM D., HİTİT M., DÖNMEZ H.
International Congress Molecular Medicine, 20 - 22 May 2015, (Summary Text)
2015
201512. Nerium oleander distillate effect on gastric cancer
DÖNMEZ H., ÇORUM O., HİTİT M., ER A., DURNA ÇORUM D.
V. International Congress Molecular Medicine, 20 - 22 May 2015, (Summary Text)
2014
201413. Melatoninin Meme Kanser Kök Hücreleri Üzerine Etkileri
KOÇAK N., DÖNMEZ H., ACAR H.
11. Ulusal Tıbbi Genetik Kongresi, Turkey, 24 - 27 September 2014, (Summary Text)
2014
201414. Endoplasmic reticulum stress and breast cancer stem cell invasion
DÖNMEZ H., KOÇAK N.
9th International Breast Cancer Congress, 26 - 28 February 2014, (Summary Text)
Books
2025
20251. Molecular Basis of Adult-Type Diffuse Gliomas
Çekin N., Akın Ş., Tüzemen Bayyurt E. B., Dönmez H., Pınarbaşı E. (Editor)
in: Molecular Basis of Cancer, Prof. Dr. Ergün Pınarbaşı, Editor, Duvar Yayınları, İzmir, pp.65-75, 2025
Funded Projects
2017 - 2018
2017 - 2018Investigation of the effect of medicarpin on head and neck cancer cell line
Project Supported by Higher Education Institutions , BAP Research Project
Kalaycı A.(Executive), Dönmez H., Hitit M.
2013 - 2014
2013 - 2014Investigation of the apoptotic and differentiation effects of melatonin on breast cancer stem cells
TUBITAK Project , 1002 - Quick Support Program
Koçak N.
2012 - 2013
2012 - 2013Investigation of microRNA expression profile depending on pregnancy in mare endometrium
TUBITAK Project , 1001 - Program for Supporting Scientific and Technological Research Projects
Kurar E., Atlı M. O., Kayış S. A., Semacan A.
Patent
2014
2014