METHYLATION OF THE E-CADHERIN (ECAD) GENE IN CLEAR CELL RENAL CELL CARCINOMA (CCRCC)

Kitapci A., Daştan T., Dündar G., Pektaş A. N., Durna Daştan S., Korğalı E., ...More

FRESENIUS ENVIRONMENTAL BULLETIN, vol.29, pp.85-91, 2020 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 29
  • Publication Date: 2020
  • Journal Name: FRESENIUS ENVIRONMENTAL BULLETIN
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Aerospace Database, Agricultural & Environmental Science Database, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), CAB Abstracts, Chemical Abstracts Core, Communication Abstracts, Environment Index, Geobase, Greenfile, Metadex, Pollution Abstracts, Veterinary Science Database, Civil Engineering Abstracts
  • Page Numbers: pp.85-91
  • Sivas Cumhuriyet University Affiliated: Yes

Abstract

Clear cell renal carcinoma is one of the most common sub-types of renal cell cancer. Methylation is the leading type of epigenetic changes. Many studies in the field emphasized that hypermethylation of some genes is efficient on the formation of many cancer types. In this study, the aim is to analyze DNA methylation, one of the epigenetic changes in the ECAD gene of renal cell carcinoma (RCC) patients, and to determine the relations by comparing the present epigenetic features with clinic-pathologic parameters.