HIGH MOBILITY GROUP BOX-1 LEVELS IN SCHIZOPHRENIA: POTENTIAL BIOMARKER OF REMISSION PHASE
JOURNAL OF MEDICAL BIOCHEMISTRY, cilt.40, sa.3, ss.295-301, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 40 Sayı: 3
- Basım Tarihi: 2021
- Doi Numarası: 10.5937/jomb0-28108
- Dergi Adı: JOURNAL OF MEDICAL BIOCHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, Central & Eastern European Academic Source (CEEAS), EMBASE, Veterinary Science Database, Directory of Open Access Journals
- Sayfa Sayıları: ss.295-301
- Anahtar Kelimeler: schizophrenia, HMGB-1, remission and acute exacerbation phase, HYPOTHESIS, PSYCHOSIS, HMGB1
- Sivas Cumhuriyet Üniversitesi Adresli: Evet
Özet
Background: Schizophrenia is a chronic mental disorder, characterized byacute exacerbation and remission phases.Immune system has a role in the pathophysiology of schizophrenia. High mobility group box-1 (HMGB-1) is a macrophage secreted protein activating immune cells to produce cytokines. The aim of this study was to evaluate HMGB-1 levels among patients with schizophrenia both in acute exacerbation and remission phases.