Akademik Veri Yönetim Sistemi
1st INTERNATIONAL HEALTH SCIENCE and LIFE CONGRESS, Burdur, Türkiye, 2 - 05 Mayıs 2018, ss.546
Green tea is one of the world's most popular drinks. Obesity and many diseases are believed to have beneficial effects in the prevention and treatment of these diseases. The anti-obesity effects of green tea are mainly attributed to the polyphenol content. The main ingredients of green tea are catechins such as epigallocatechin gallate (EGCG), epigallocatechin, epicatechin gallate. EGCG is the most common catechin in green tea and considered to be the most effective bioactive component in body weight reduction by reducing adipocyte differentiation and proliferation during lipogenesis. The antiobesity effect of green tea and polyphenolic components has been explained by different mechanisms such as modulation of pancreatic lipase, inhibition of de novo lipogenesis, increase of fatty acid oxidation and thermogenesis in brown fat tissue. Green tea extract (rich in catechins and EGCG) reduces obesity and mild inflammation and in mice fed on a high fat diet, in addition to this anti-inflammatory effect, it inhibited the whitening of brown fat and contributed to the browning of the white fat tissue.In a study by Chen N et al, green tea and EGCG were found to reduce body fat and increase lean mass in rats fed a high fat diet. In another study, mice fed a high-fat diet were found to have reduced obesity-associated liver fat markers, fecal lipid augmentation, modifying body weight gain by increasing both the skeletal muscle genes involved in fat oxidation and reducing fat absorption from the diet. As a result, green tea capsule forms have been used in this study. Future studies are needed to better understand the contribution of green tea to its natural form in green tea studies and the contribution of green tea extract to antiobesity when natural and capsule forms are thought to be in different matrices and bioactivity.