How do arbidol and its analogs inhibit the SARS-CoV-2?

Aktas A., Tuzun B., Kafa T. A. H. , Sayin K., Ataseven H.

Bratislavske lekarske listy, vol.121, no.10, pp.705-711, 2020 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 121 Issue: 10
  • Publication Date: 2020
  • Doi Number: 10.4149/bll_2020_115
  • Journal Name: Bratislavske lekarske listy
  • Journal Indexes: Science Citation Index Expanded, Scopus, Academic Search Premier, EMBASE, MEDLINE
  • Page Numbers: pp.705-711
  • Keywords: SARS-CoV-2, spike glycoprotein, hemagglutinin esterase, arbidol, in silico, VIRUS, SPIKE, DOCKING, PROTEIN, GLIDE


BACKGROUND: COVID-19 is not fully known and causes severe inflammation and cytokine storm. It has many symptoms, such as: fever, sore throat, headache, dyspnoea, and diarrhoea. Arbidol was used in the treatment of COVID19, which was the most critical health problem in the world. However, the desired recovery was not achieved with Arbidol. Many countries still use this drug in the treatment of COVID19.