The Effect of Melatonin on Bone Loss, Diabetic Control, and Apoptosis in Rats With Diabetes With Ligature-Induced Periodontitis

BALCI YÜCE H., KARATAŞ Ö., Turkal H. A., Gorgun E., OCAKLI S., Benli I., ...Daha Fazla

JOURNAL OF PERIODONTOLOGY, cilt.87, sa.4, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 87 Sayı: 4
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1902/jop.2015.150315
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Experimental diabetes mellitus, iNOS, melatonin, periodontitis, TRAP, NITRIC-OXIDE SYNTHASE, OSTEOBLAST-LIKE CELLS, OXIDATIVE STRESS, REACTIVE OXYGEN, LIPID-PEROXIDATION, RODENT MODEL, MELLITUS, INFLAMMATION, ACTIVATION, DISEASE
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Background: The aim of this study examines the effect of systemic melatonin administration on proin-flammatory cytokine levels, apoptosis, alveolar bone loss (ABL), lipid metabolism, and diabetic control in in rats with diabetes mellitus (DM) and ligature-induced periodontitis.