Increasing the efficiency of internal combustion engines using fossil fuels also plays an important role in reaching the greenhouse gas emission values determined by international agreements due to global warming. One of the effective ways to increase combustion efficiency in internal combustion engines is to keep the in-cylinder temperature under control as much as possible. For this reason, it is desired that engines are cooled and reach the required high temperature only at the required time. The cooling system is very important for the strength of the engine parts. With the new system, the corrosive effect of the water used in the cooling system can be prevented. In addition, the development of a more sensitive cooling system can offer automotive manufacturers many opportunities to intervene in cylinder temperatures, which may even mean setting different parameters for engine performance. No negative conclusions have been reached regarding the use of refrigerants in internal combustion engines.