Effect of Capparis spinosa L. on cognitive impairment induced by D-galactose in mice via inhibition of oxidative stress

TURGUT N. H., KARA H., ARSLANBAŞ E., MERT D. G., TEPE B., GÜNGÖR H.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.45, no.5, pp.1127-1136, 2015 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 5
  • Publication Date: 2015
  • Doi Number: 10.3906/sag-1405-95
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1127-1136
  • Keywords: Alzheimer disease, Capparis spinosa L., D-galactose, oxidative stress, cognitive impairment, SPECIES GROWING WILD, LIPID-PEROXIDATION, LYOPHILIZED EXTRACT, ALZHEIMERS-DISEASE, SYRINGIC ACID, SEED OILS, BRAIN, ANTIOXIDANT, MARKERS, MEMORY
  • Sivas Cumhuriyet University Affiliated: Yes

Abstract

Background/aim: To determine the phenolic acid levels and DNA damage protection potential of Capparis spinosa L. seed extract and to investigate the effect of the extract on cognitive impairment and oxidative stress in an Alzheimer disease mice model.