Significant association between MDM2 T309G polymorphism and colorectal cancer


Atabey M., TAŞ A. , Sari I., BOSTANCI M. E. , TOPÇU Ö. , SİLİĞ Y.

JOURNAL OF BUON, vol.24, no.3, pp.1137-1142, 2019 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 3
  • Publication Date: 2019
  • Title of Journal : JOURNAL OF BUON
  • Page Numbers: pp.1137-1142

Abstract

Purpose: The Murine double minute 2 (MDM2) gene plays a crucial role in regulating and suppressing the function of apoptotic pathway. We investigated the relationship between MDM2 gene SNP309 (T309G) (rs2279744) polymorphism and colorectal cancer (CRC) in a Turkish population.