Positive effects of angiotensin-converting enzyme (ACE) inhibitor, captopril, on pentylenetetrazole-induced epileptic seizures in mice


TAŞTEMUR Y., Gumus E., ERGÜL M., Ulu M., AKKAYA R., Ozturk A., ...More

TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, vol.19, no.3, pp.637-643, 2020 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 3
  • Publication Date: 2020
  • Doi Number: 10.4314/tjpr.v19i3.26
  • Journal Name: TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, International Pharmaceutical Abstracts, Veterinary Science Database, Directory of Open Access Journals
  • Page Numbers: pp.637-643
  • Keywords: Captopril, Angiotensin-converting enzyme, Epilepsy, Pentylenetetrazole, Neuronal damage, DAMAGE, SYSTEM
  • Sivas Cumhuriyet University Affiliated: Yes

Abstract

Purpose: To evaluate the effects of an angiotensin-converting enzyme (ACE) inhibitor, captopril, on pentylenetetrazole (PTZ)-induced seizures and post-seizure hippocampal injury.