Positive effects of angiotensin-converting enzyme (ACE) inhibitor, captopril, on pentylenetetrazole-induced epileptic seizures in mice

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TAŞTEMUR Y., Gumus E., ERGÜL M., Ulu M., AKKAYA R., Ozturk A., ...More

TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, vol.19, no.3, pp.637-643, 2020 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 19 Issue: 3
• Publication Date: 2020
• Doi Number: 10.4314/tjpr.v19i3.26
• Journal Name: TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, International Pharmaceutical Abstracts, Veterinary Science Database, Directory of Open Access Journals
• Page Numbers: pp.637-643
• Keywords: Captopril, Angiotensin-converting enzyme, Epilepsy, Pentylenetetrazole, Neuronal damage, DAMAGE, SYSTEM
• Sivas Cumhuriyet University Affiliated: Yes

Abstract

Purpose: To evaluate the effects of an angiotensin-converting enzyme (ACE) inhibitor, captopril, on pentylenetetrazole (PTZ)-induced seizures and post-seizure hippocampal injury.