STOX1 gene Y153H polymorphism is associated with early-onset preeclampsia in Turkish population

PINARBAŞI E. , ÇEKİN N. , Bildirici A. E. , Akin S., YANIK A.

GENE, vol.754, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 754
  • Publication Date: 2020
  • Doi Number: 10.1016/j.gene.2020.144894
  • Title of Journal : GENE


Preeclampsia (PE) is a disease of pregnancy that causes of maternal and prenatal morbidity worldwide. Studies indicate that variations in STOX1 gene may be a direct risk factor to PE but controversial results regarding the relationship of Y153H variation in the second exon of STOX1 gene with PE have been ongoing since 2005. The aim of this study was to identify if there is any correlation between Y153H polymorphisms and PE in Turkish preeclampsia patients.