Akademik Veri Yönetim Sistemi
10th International Medicine and Health Sciences Researches Congress, Ankara, Türkiye, 27 - 28 Ağustos 2022, ss.431-438
Introduction: In this study, it was aimed to compare the mortality predictive power of systemic inflammatory response index (SIRI) and systemic immune inflammation index (SIII) in geriatric intensive care patients who developed stroke due to acute cerebral infarction. Materials and Method: This retrospective, single-center study included 100 patients over 65 years old who were admitted to intensive care with the diagnosis of acute cerebral infarction. The study was approved by the institutional ethics committee (Sivas Cumhuriyet University) (decision date: 27/07/2022, number: 2022-07/14). Neutrophil count (N), lymphocyte count (L), platelet count (P) and monocyte count (M) obtained from hemogram examination were recorded. Using these cell numbers, the SIRI for each patient was calculated and recorded with NxM/L and SIII; PxN/L formulas. Results: When cut-off >2.92 is taken for SIRI, 100% sensitivity and 95.83% specificity are obtained. When cut-off >896 is taken for SIII, 97.37% sensitivity and 75% specificity are obtained. According to the COX regression analysis, while the order >2.92 increases mortality 28,569 times (p=0.01), the SIII>896 increases mortality 7,818 times (p=0.004). Conclusion: High SIRI and SIII values are associated with increased mortality in patients with acute severe ischemic stroke in the geriatric patient group. Although the specificity of SIRI was found to be higher than SIII, we think that both indices can be used in clinical practice.