No association of polymorphisms in the glutathione S-transferase genes with pre-eclampsia, eclampsia and HELLP syndrome in a Turkish population.


Cetin M., Pinarbasi E., Percin F., Akgun E., Percin S., Pinarbasi H., ...Daha Fazla

The journal of obstetrics and gynaecology research, cilt.31, sa.3, ss.236-41, 2005 (SCI-Expanded) identifier identifier identifier

Özet

Aim: There is substantial evidence that genetic factors play a role in pre-eclampsia. The aim of this study was to determine whether genetic variability in the encoding of genes for glutathione S-transferase M1 (GSTM1) and glutathione S-transferase T1 (GSTT1) contributes to individual differences in susceptibility to pre-eclampsia, eclampsia, or hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome).