Akademik Veri Yönetim Sistemi
6th International Congress on Veterinary and Animal Science, Antalya, Türkiye, 02 Eylül 2021
Salvia tomentosa, which is widespread in flora of Turkey, has been used in traditional
medicine for various therapeutic purposes. The aim of this study was to evaluate the in vitro
antibacterial activity of ethanolic extract of S. tomentosa against Staphylococcus aureus,
Escherichia coli, and Pseudomonas aeruginosa. Antibacterial activities against these strains
were evaluated using the microdilution method to determine minimum inhibitory
concentration (MIC) and minimum bactericidal concentration (MBC) and agar well diffusion
method to determine zone of inhibition. Maximum zones of inhibition were found in the
following order S. aureus (16.05±0.34 mm) and E. coli (15.075±0.26 mm). The ethanolic
extract did not show inhibition zone against P. aeruginosa at all treated concentrations of the
extract (10% -0.625%). While MIC values of the ethanolic extract for S. aureus, E. coli and P.
aeruginosa were 0.31%, 0.63% and >2.5% for 24 h, MBC values were 2.5%, 2.5% and
>2.5%, respectively. The results showed that the ethanolic extract of S. tomentosa exhibited
antibacterial activity against these pathogens, except P. aeruginosa, at high concentrations.