Frequency of the mdr-1 C > T gene polymorphism in patients with COPD

DOĞAN Ö. T., KATRANCIOĞLU N., KARAHAN O., Sanli G. C., ZORLU A., MANDUZ Ş.

CLINICS, cilt.65, sa.11, ss.1115-1117, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 65 Sayı: 11
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1590/s1807-59322010001100010
  • Dergi Adı: CLINICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1115-1117
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

BACKGROUND AND AIM: The multi-drug resistant-1 (MDR-1) gene is located on human chromosome 7 and encodes a glycosylated membrane protein that is a member of the ATP-binding cassette transporters superfamily. The aim of the study was to reveal the role of the C3435T MDR-1 gene polymorphism in chronic obstructive pulmonary disease.