Frequency of the mdr-1 C > T gene polymorphism in patients with COPD


DOĞAN Ö. T. , KATRANCIOĞLU N. , KARAHAN O., Sanli G. C. , ZORLU A. , MANDUZ Ş.

CLINICS, vol.65, no.11, pp.1115-1117, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 65 Issue: 11
  • Publication Date: 2010
  • Doi Number: 10.1590/s1807-59322010001100010
  • Title of Journal : CLINICS
  • Page Numbers: pp.1115-1117

Abstract

BACKGROUND AND AIM: The multi-drug resistant-1 (MDR-1) gene is located on human chromosome 7 and encodes a glycosylated membrane protein that is a member of the ATP-binding cassette transporters superfamily. The aim of the study was to reveal the role of the C3435T MDR-1 gene polymorphism in chronic obstructive pulmonary disease.