Effect of Non surgical Periodontal Treatment on Gingival Crevicular Fluid Interleukin-1beta and Interleukin-37 in Different Periodontal Diseases


Gorgun E., Toker H., POYRAZ Ö.

MEANDROS MEDICAL AND DENTAL JOURNAL, cilt.22, ss.110-118, 2021 (ESCI) identifier identifier

Özet

Objective: Interleukin-37 (IL-37), which is a natural inhibitor of innate immunity, is correlated with chronic inflammation and some autoimmune diseases. Proinflammatory cytokines, for example, interleukin-1beta (IL-1 beta), which plays a key part in the periodontium, can induce IL-37. This study aimed to investigate the effect of non-surgical periodontal treatment on gingival crevicular fluid (GCF) IL-37 and IL-1 beta levels in generalized aggressive periodontitis (G-AgP) and generalized chronic periodontitis (GCP).