Effect of Non surgical Periodontal Treatment on Gingival Crevicular Fluid Interleukin-1beta and Interleukin-37 in Different Periodontal Diseases


Gorgun E. P. , Toker H. , POYRAZ Ö.

MEANDROS MEDICAL AND DENTAL JOURNAL, vol.22, pp.110-118, 2021 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 22
  • Publication Date: 2021
  • Doi Number: 10.4274/meandros.galenos.2021.09821
  • Title of Journal : MEANDROS MEDICAL AND DENTAL JOURNAL
  • Page Numbers: pp.110-118

Abstract

Objective: Interleukin-37 (IL-37), which is a natural inhibitor of innate immunity, is correlated with chronic inflammation and some autoimmune diseases. Proinflammatory cytokines, for example, interleukin-1beta (IL-1 beta), which plays a key part in the periodontium, can induce IL-37. This study aimed to investigate the effect of non-surgical periodontal treatment on gingival crevicular fluid (GCF) IL-37 and IL-1 beta levels in generalized aggressive periodontitis (G-AgP) and generalized chronic periodontitis (GCP).