PDA-TOLERATE Trial: An Exploratory Randomized Controlled Trial of Treatment of Moderate-to-Large Patent Ductus Arteriosus at 1 Week of Age


Clyman R. I. , Liebowitz M., Kaempf J., Erdeve O., Bulbul A., Hakansson S., ...Daha Fazla

JOURNAL OF PEDIATRICS, cilt.205, ss.41-54, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 205
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.jpeds.2018.09.012
  • Dergi Adı: JOURNAL OF PEDIATRICS
  • Sayfa Sayıları: ss.41-54

Özet

Objective To compare early routine pharmacologic treatment of moderate-to-large patent ductus arteriosus (PDA) at the end of week 1 with a conservative approach that requires prespecified respiratory and hemodynamic criteria before treatment can be given.