Bioconjugation of Magnetic Iron Oxide Nanoparticles and Cross-Linked Enzyme Aggregates: Characterization and Comparison of CLEAs and Magnetic CLEAs


CURRENT NANOSCIENCE, vol.13, no.2, pp.149-158, 2017 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 2
  • Publication Date: 2017
  • Doi Number: 10.2174/1573413712666161018115439
  • Title of Journal : CURRENT NANOSCIENCE
  • Page Numbers: pp.149-158


Background: The separation of enzymes from the bio-product medium constitutes a significant part of total process cost. Therefore, it is of crucial importance that the separation processes for enzymes be specially developed. In this study, the advantages of cross-linked enzyme aggregates (CLEAs) and magnetic iron oxide nanoparticles (MIONPs) have been combined in magnetic CLEAs matrix.