Evaluation of Apoptosis Markers Caspas-8, Cytochrome C Levels in PCOS Patients

SARIAKÇALI B., DUMAN G.

Pakistan Journal of Medical and Health Sciences, cilt.16, sa.1, ss.574-578, 2022 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 1
  • Basım Tarihi: 2022
  • Doi Numarası: 10.53350/pjmhs22161574
  • Dergi Adı: Pakistan Journal of Medical and Health Sciences
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, EMBASE
  • Sayfa Sayıları: ss.574-578
  • Anahtar Kelimeler: PCOS, Apoptosis, Caspase-8, Cytochrome-C, POLYCYSTIC-OVARY-SYNDROME, NF-KAPPA-B, OXIDATIVE STRESS, CANCER, INFLAMMATION, SURVIVAL, INSIGHTS, MOLECULE, CELLS, WOMEN
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Background: Apoptosis is defined as a programmed cell death that eliminates dysfunctional, damaged, and fulfilled cells as a result of a certain stimulus. PCOS, IR, ovarian hyperandrogenism, hyperinsulinemia, and alterations in follicular endocrine signaling may impact the activation, growth, survival, and atresia of follicles. As a result of this impact, polycystic morphology may be observed in the ovaries, follicle development may be inhibited, and anovulation may occur.