An Investigation of the Effects of Curcumin on the Changes in the Central Nervous System of Rats Exposed to Aroclor 1254 in the Prenatal Period

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Atıf İçin Kopyala

ALÇIĞIR M. E., DOĞAN H. O., Dikmen B. Y., Dogan K., Vural S. A., YILMAZ F. M., ...Daha Fazla

CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS, cilt.17, sa.2, ss.132-143, 2018 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 17 Sayı: 2
• Basım Tarihi: 2018
• Doi Numarası: 10.2174/1871527317666180315170146
• Dergi Adı: CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.132-143
• Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Background & Objective: Aroclor 1254 is a widespread toxic compound of Polychlorinated Biphenyls (PCBs), which can create significant nervous problems. No remedies have been found to date. The aim of this study was to reveal the damage that occurs in the central nervous system of rat pups exposed to Aroclor 1254 in the prenatal period and to show the inhibiting effect of curcumin, which is a strong anti-oxidant and neuroprotective substance.