The effects of L type calcium channels on the electroencephalogram recordings in WAG/RIJ rat model of absence epilepsy


Durmus N., Kaya T., Gulturk S., Demir T., Parlak M., Altun A.

European Review for Medical and Pharmacological Sciences, vol.17, no.9, pp.1149-1154, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 9
  • Publication Date: 2013
  • Title of Journal : European Review for Medical and Pharmacological Sciences
  • Page Numbers: pp.1149-1154

Abstract

BACKGROUND: Epilepsy is one of the most important central nervous system disorder and 1% of the total world population suffers from this disorder which require a chronic drug treatment. Most of the researchers suggested that excessive calcium entry into neurons is the main triggering event in the initiation of epileptic discharges but the role of L type calcium channels has not been clarified in absence epilepsy.