The effects of L type calcium channels on the electroencephalogram recordings in WAG/RIJ rat model of absence epilepsy

Durmus N., Kaya T., Gulturk S., Demir T., Parlak M., Altun A.

European Review for Medical and Pharmacological Sciences, cilt.17, sa.9, ss.1149-1154, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 9
  • Basım Tarihi: 2013
  • Dergi Adı: European Review for Medical and Pharmacological Sciences
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1149-1154
  • Anahtar Kelimeler: Epilepsy, WAG/Rij rats, L type calcium channels, NEW-ONSET, CHILDREN, MECHANISMS
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

BACKGROUND: Epilepsy is one of the most important central nervous system disorder and 1% of the total world population suffers from this disorder which require a chronic drug treatment. Most of the researchers suggested that excessive calcium entry into neurons is the main triggering event in the initiation of epileptic discharges but the role of L type calcium channels has not been clarified in absence epilepsy.