Therapeutic plasma exchange in patients with thrombotic thrombocytopenic purpura: A retrospective multicenter study


KORKMAZ S. , Keklik M., Sivgin S., YILDIRIM R., TOMBAK A., Kaya M. E. , ...More

TRANSFUSION AND APHERESIS SCIENCE, vol.48, no.3, pp.353-358, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 3
  • Publication Date: 2013
  • Doi Number: 10.1016/j.transci.2013.04.016
  • Title of Journal : TRANSFUSION AND APHERESIS SCIENCE
  • Page Numbers: pp.353-358

Abstract

Thrombotic thrombocytopenic purpura (TIT) is a particular form of thrombotic microangiopathy typically characterized by thrombocytopenia, microangiopathic hemolytic anemia, fever, neurological abnormalities, and renal dysfunction. UP requires a rapid diagnosis and an adapted management in emergency. Daily sessions of therapeutic plasma exchange (TPE) remain the basis of management of UP. Also, UP is a rare disease that is fatal if it is not treated. TPE has resulted in excellent remission and survival rates in UP patients.