Therapeutic plasma exchange in patients with thrombotic thrombocytopenic purpura: A retrospective multicenter study

KORKMAZ S., Keklik M., Sivgin S., YILDIRIM R., TOMBAK A., Kaya M. E., ...More

TRANSFUSION AND APHERESIS SCIENCE, vol.48, no.3, pp.353-358, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 3
  • Publication Date: 2013
  • Doi Number: 10.1016/j.transci.2013.04.016
  • Journal Name: TRANSFUSION AND APHERESIS SCIENCE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.353-358
  • Sivas Cumhuriyet University Affiliated: Yes

Abstract

Thrombotic thrombocytopenic purpura (TIT) is a particular form of thrombotic microangiopathy typically characterized by thrombocytopenia, microangiopathic hemolytic anemia, fever, neurological abnormalities, and renal dysfunction. UP requires a rapid diagnosis and an adapted management in emergency. Daily sessions of therapeutic plasma exchange (TPE) remain the basis of management of UP. Also, UP is a rare disease that is fatal if it is not treated. TPE has resulted in excellent remission and survival rates in UP patients.