Objective: The main purpose of the study is to evaluate the job satisfaction and stress of the health professionals working in a state hospital according to their sociodemographic characteristics and to reveal whether there are any relations between them. Methods: Data have been obtained by means of a form including Minnesota Job Satisfaction Scale, Perceived Job Stress Scale and sociodemographic variables on totally 180 health professionals who are employed in Sivas Numune Hospital. Findings: In our study, it was evaluated that the job satisfaction points of the males were higher when compared to females, those of post-graduates were higher than those of graduates and undergraduates and those of doctors were higher than those of nurses in a statistically important level. The external satisfaction points of the group over 45 when compared to that of the group under 34 and those of other health professionals when compared to nurses were found to be statistically higher. It was found that job stress points of women were higher compared to males, those of the graduates of secondary education, undergraduates and graduates were higher than those of postgraduates, and the job stress points of the nurses were higher than those of doctors and other health professionals. There is a meaningful negative correlation between job satisfaction and job stress. No statistically important difference was found with reference to their marital status, whether they have children and their work years. Results: In our study, job satisfaction and job stress of the health care professionals were studied sociodemographically. In healthcare institutions, besides the satisfaction of the patients, it is also important to deal with and find solutions to the problems of the health care personnel for the establishment of job satisfaction and eliminate job stress.