ANALYSIS OF IL-6, IL-10 AND NF-kappa B GENE POLYMORPHISMS IN AGGRESSIVE AND CHRONIC PERIODONTITIS


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TOKER H. , Gorgun E. P. , KORKMAZ E. M.

CENTRAL EUROPEAN JOURNAL OF PUBLIC HEALTH, cilt.25, ss.157-162, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 25 Konu: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.21101/cejph.a4656
  • Dergi Adı: CENTRAL EUROPEAN JOURNAL OF PUBLIC HEALTH
  • Sayfa Sayıları: ss.157-162

Özet

Objective: Pro-inflammatory cytokines, interleukin-6 (IL-6), demonstrated to be suppressed by interleukin-10 (IL-10) are known to be regulated by the transcription factor nuclear factor-kappa B(NF-kappa B). The aim of this study was to ascertain the association between genetic polymorphism of these genes (IL-6(-174), IL-10(-597) and NF-kappa B1-94ins/del)) and chronic/aggressive periodontitis.