CENTRAL EUROPEAN JOURNAL OF PUBLIC HEALTH, vol.25, no.2, pp.157-162, 2017 (Journal Indexed in SCI)
Article / Article
Title of Journal :
CENTRAL EUROPEAN JOURNAL OF PUBLIC HEALTH
periodontitis, polymorphism, NF-kappa B, IL-6, IL-10, INTERLEUKIN-10 GENE, PROMOTER POLYMORPHISMS, INFLAMMATORY DISEASES, NFKB1 PROMOTER, ASSOCIATION, SUSCEPTIBILITY, METAANALYSIS, POPULATION, EXPRESSION, HAPLOTYPE
Objective: Pro-inflammatory cytokines, interleukin-6 (IL-6), demonstrated to be suppressed by interleukin-10 (IL-10) are known to be regulated by the transcription factor nuclear factor-kappa B(NF-kappa B). The aim of this study was to ascertain the association between genetic polymorphism of these genes (IL-6(-174), IL-10(-597) and NF-kappa B1-94ins/del)) and chronic/aggressive periodontitis.