Akademik Veri Yönetim Sistemi
Journal of advances in vetbio science and techniques, cilt.8, sa.2, ss.1-5, 2023 (Hakemli Dergi)
The aim of this study is to determine the effects of resveratrol used in adding it to drinking water. The study was conducted with 24 20-day-old male rats of the Wistar albino breed. The study design was determined as one control and two trial groups (each group with 2 parallels and each parallel with 4 rats). The first group was given a basal ration and drinking water. The second group was given the basal ration and drinking water with 10 mg/kg resveratrol; and the third group was given the basal ration and drinking water 20 mg/kg resveratrol.
In serum biochemistry parameters, significant decreases were observed in serum AST enzyme activity, BUN, albumin, total protein and globulin concentrations and increase in albumin/globulin ratio in groups given resveratrol (p < 0.05). Regardless of the dose, an increase in the concentration of GSH from the antioxidant parameters was observed in the liver; In the kidney, an increase was observed in the Res10 group. In addition, a decrease in muscle SOD activity and an increase in muscle and kidney CAT activity were observed. A decrease was observed in MDA concentrations, which is a parameter of lipid peroxidation in the kidney. As a result, it was determined in the present study that resveratrol has antioxidant effects regardless of the way of use, and it was concluded that this additive can be used for various purposes.