The influence of quercetin on recognition memory and brain oxidative damage in a ketamine model of schizophrenia

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MERT D. G., TURGUT N. H., ARSLANBAŞ E., GÜNGÖR H., KARA H.

PSYCHIATRY AND CLINICAL PSYCHOPHARMACOLOGY, cilt.29, sa.1, ss.1-7, 2019 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1080/24750573.2018.1442670
  • Dergi Adı: PSYCHIATRY AND CLINICAL PSYCHOPHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1-7
  • Anahtar Kelimeler: Quercetin, schizophrenia, recognition memory, ketamine, antioxidant, FREE-RADICAL PATHOLOGY, COGNITIVE FUNCTION, ANTIOXIDANT, RECOLLECTION, INVOLVEMENT, FAMILIARITY, EXPRESSION, BEHAVIOR, DEFICITS, STRESS
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

OBJECTIVE: The aims of this study were to investigate the protective effect of quercetin on changes in recognition memory as assessed by the novel object recognition (NOR) test, as well as on changes in the oxidative stress levels in the hippocampus and prefrontal cortex, produced in a model of memory impairment in schizophrenia induced by administration of a subanesthetic dose of ketamine.