Do antibiotics contribute to postoperative ileus? Contractile responses of ileum smooth muscle in guinea pigs to long-term parenteral ceftriaxone and ampicillin

Ceran C., Karadas B., Kaya T., Arpacik M., Bagcivan I., Sarac B.

ANZ JOURNAL OF SURGERY, cilt.76, sa.11, ss.1023-1026, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 76 Sayı: 11
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1111/j.1445-2197.2006.03922.x
  • Dergi Adı: ANZ JOURNAL OF SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1023-1026
  • Anahtar Kelimeler: ampicillin, ceftriaxone, contractile response, ileum, SMALL-INTESTINE, IN-VITRO, PYELONEPHRITIS, TRANSMISSION, PREGNANCY, ILEAL, CA2+
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Background: Antibiotics may impair small bowel smooth muscle contractility and contribute to postoperative ileus. The aim of this study was to compare the contractile responses of ileum smooth muscle to different agonists in guinea pigs treated with ceftriaxone (Rocephin; F. Hoffman-La Roche, Kaiseraugst, Switzerland) or ampicillin (Ampisina; Mustafa Nevzat Ilac Sanayii AS, Istanbul, Turkey).