METHYLATION OF THE E-CADHERIN (ECAD) GENE IN CLEAR CELL RENAL CELL CARCINOMA (CCRCC)


Kitapci A., Daştan T. , Dündar G. , Pektaş A. N. , Durna Daştan S. , Korğalı E. , ...Daha Fazla

FRESENIUS ENVIRONMENTAL BULLETIN, cilt.29, ss.85-91, 2020 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 29
  • Basım Tarihi: 2020
  • Dergi Adı: FRESENIUS ENVIRONMENTAL BULLETIN
  • Sayfa Sayıları: ss.85-91

Özet

Clear cell renal carcinoma is one of the most common sub-types of renal cell cancer. Methylation is the leading type of epigenetic changes. Many studies in the field emphasized that hypermethylation of some genes is efficient on the formation of many cancer types. In this study, the aim is to analyze DNA methylation, one of the epigenetic changes in the ECAD gene of renal cell carcinoma (RCC) patients, and to determine the relations by comparing the present epigenetic features with clinic-pathologic parameters.