Ozone therapy holds significant potential in various areas of dentistry. It is particularly promising due to its less invasive nature compared to traditional treatment procedures. Ozone therapy has opened up new horizons in treatment methods for patients of all ages with dental conditions, and it can be applied to a wide range of intraoral hard and soft tissues. It possesses potent disinfectant properties, thereby reducing bacterial counts more specifically with minimal adverse effects. It reduces treatment duration and patient discomfort, thereby enhancing patient compliance and making it more acceptable for patients. It is especially suitable for patients who fear drilling and refuse traditional treatment methods. However, the effective use of ozone in routine dentistry has not yet been universally accepted due to inadequate knowledge, lack of education, and conflicting evidence in the literature. Therefore, for ozone therapy to be applied as a standard treatment method in dentistry, larger sample sizes, sufficient follow-up periods, standard measurements, and well- structured analyses with double/triple-blind randomized controlled trials are needed.