Gulhane Medical Journal, cilt.68, sa.1, ss.16-23, 2026 (Scopus, TRDizin)
Aims: We aimed to investigate whether the Assessment of SpondyloArthritis International Society Health Index (ASAS HI) correlates with scales assessing overall health status, disease activity, spinal mobility, quality of life, and functional capacity in individuals with ankylosing spondylitis (AS). Methods: This cross-sectional study included patients with AS diagnosed according to the 2010 ASAS classification criteria. ASAS HI, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Ankylosing Spondylitis Disease Activity Score-C-Reactive Protein (ASDAS-CRP), Bath Ankylosing Spondylitis Functional Index (BASFI), Dougados Functional Index (DFI), Bath Ankylosing Spondylitis Metrology Index, Bath Ankylosing Spondylitis Patient Global Score (BAS-G), Visual Analog Scale (VAS) for pain and morning stiffness scores, Ankylosing Spondylitis Quality of Life (ASQoL), EuroQol-5D (EQ-5D), and EQ VAS were measured. Statistical analyses were conducted to examine correlations between the ASAS HI and other measurement instruments. Results: A cohort of 141 patients (84 males and 57 females) with a mean age of 39.02±12.16 years was included in the study. ASAS HI was positively correlated with BASDAI, ASDAS-CRP, and ASDAS-ESR (p<0.001, r=0.63, r=0.61, r=0.64). ASAS HI demonstrated strong positive correlations with BASFI and DFI (p<0.001, r=0.71, r=0.72), and a significant negative correlation with EQ-5D (p<0.001, r=-0.67). Additionally, notable positive associations were observed with ASQoL (p<0.001, r=0.79) and BAS-G (p<0.001, r=0.63). Conclusions: The ASAS HI may serve as a measure of overall health in patients with AS, provide additional insights alongside assessments of disease severity, functional ability, and well-being, and facilitate longitudinal monitoring of treatment outcomes.