This study, investigate the condition factors of some Cyprinid fishes in Kilickaya Reservoir, Central Anatolian region of Turkey. The obtained results were compared with other studies from different habitats in Turkey. Cyprinus carpio (1.7856.+/- 0.2603) has the greatest mean condition factor followed by Leuciscus cephalus (1.6373 +/- 0.1483), Capoeta sieboldii (1.1596 +/- 0.1186), Capoeta tinca (1.1375 +/- 0.0991) and Barbus plebejus(1.1336 +/- 0.1083). According to the results, condition factors of some Cyprinid fishes are shown that a good level of nutrition of fish and nutritional capacity in Kilickaya Reservoir. Knowledge of condition factors of some Cyprinid fishes are important for adequate management and maintenance of the bio-ecological equilibrium of the ecosystem in Kilickaya Reservoir.