Morphometric and histopathological evaluation of the effect of grape seed proanthocyanidin on alveolar bone loss in experimental diabetes and periodontitis

Toker, H.; Yuce, H.; Alpan, A.; Gevrek, F.; Elmastas, M.

doi:10.1111/jre.12536

Morphometric and histopathological evaluation of the effect of grape seed proanthocyanidin on alveolar bone loss in experimental diabetes and periodontitis

Copy For Citation

Toker H., Yuce H. B. , Alpan A. L. , Gevrek F., Elmastas M.

JOURNAL OF PERIODONTAL RESEARCH, vol.53, no.3, pp.478-486, 2018 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 53 Issue: 3
Publication Date: 2018
Doi Number: 10.1111/jre.12536
Title of Journal : JOURNAL OF PERIODONTAL RESEARCH
Page Numbers: pp.478-486

Abstract

Objective: Grape seed proanthocyanidine extract (GSPE) is a strong antioxidant derived from the grape seeds (Vitis vinifera, Terral J.F.) and has a polyphenolic structure with a wide range of biological activity. The aim of the present study was to evaluate the effects of GSPE on alveolar bone loss and histopathological changes in rats with diabetes mellitus and ligature-induced periodontitis.