Morphometric and histopathological evaluation of the effect of grape seed proanthocyanidin on alveolar bone loss in experimental diabetes and periodontitis

Toker, H.; Yuce, H.; Alpan, A.; Gevrek, F.; Elmastas, M.

doi:10.1111/jre.12536

Morphometric and histopathological evaluation of the effect of grape seed proanthocyanidin on alveolar bone loss in experimental diabetes and periodontitis

Atıf İçin Kopyala

Toker H., Yuce H. B. , Alpan A. L. , Gevrek F., Elmastas M.

JOURNAL OF PERIODONTAL RESEARCH, cilt.53, ss.478-486, 2018 (SCI İndekslerine Giren Dergi)

Cilt numarası: 53 Konu: 3
Basım Tarihi: 2018
Doi Numarası: 10.1111/jre.12536
Dergi Adı: JOURNAL OF PERIODONTAL RESEARCH
Sayfa Sayıları: ss.478-486

Özet

Objective: Grape seed proanthocyanidine extract (GSPE) is a strong antioxidant derived from the grape seeds (Vitis vinifera, Terral J.F.) and has a polyphenolic structure with a wide range of biological activity. The aim of the present study was to evaluate the effects of GSPE on alveolar bone loss and histopathological changes in rats with diabetes mellitus and ligature-induced periodontitis.