microRNA-143 and-223 in obesity

Kilic I. D., Dodurga Y., Uludag B., Alihanoglu Y. I., Yildiz B. S., Enli Y., ...Daha Fazla

GENE, cilt.560, sa.2, ss.140-142, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 560 Sayı: 2
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.gene.2015.01.048
  • Dergi Adı: GENE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.140-142
  • Anahtar Kelimeler: Obesity, microRNA-143, microRNA-223, ADIPOSE-TISSUE, CIRCULATING MICRORNAS, SUBCUTANEOUS ADIPOSE, EXPRESSION, ADIPOGENESIS, INFLAMMATION, ACTIVATION, MIR-223
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Background: Obesity alters endocrine and metabolic functions of adipose tissue and has been recognized as a chronic inflammatory disease, which in turn may contribute to the development of insulin resistance, type 2 diabetes, obesity-associated vasculopathy and cardiovascular disease. The pathogenesis of obesity involves many regulatory pathways including transcriptional regulatory networks, including microRNAs.