HIGH MOBILITY GROUP BOX-1 LEVELS IN SCHIZOPHRENIA: POTENTIAL BIOMARKER OF REMISSION PHASE

YILMAZ N., YELBOĞA Z., YILMAZ Y., DEMİRPENÇE Ö.

JOURNAL OF MEDICAL BIOCHEMISTRY, cilt.40, sa.3, ss.295-301, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 3
  • Basım Tarihi: 2021
  • Doi Numarası: 10.5937/jomb0-28108
  • Dergi Adı: JOURNAL OF MEDICAL BIOCHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, Central & Eastern European Academic Source (CEEAS), EMBASE, Veterinary Science Database, Directory of Open Access Journals
  • Sayfa Sayıları: ss.295-301
  • Anahtar Kelimeler: schizophrenia, HMGB-1, remission and acute exacerbation phase, HYPOTHESIS, PSYCHOSIS, HMGB1
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Background: Schizophrenia is a chronic mental disorder, characterized byacute exacerbation and remission phases.Immune system has a role in the pathophysiology of schizophrenia. High mobility group box-1 (HMGB-1) is a macrophage secreted protein activating immune cells to produce cytokines. The aim of this study was to evaluate HMGB-1 levels among patients with schizophrenia both in acute exacerbation and remission phases.