A deep eutectic solvent-based microextraction method for the extraction of Erythrosine from complex samples: statistical approach

FESLİYAN S., ELİK A.

Journal of Food Composition and Analysis, cilt.135, 2024 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 135
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1016/j.jfca.2024.106605
  • Dergi Adı: Journal of Food Composition and Analysis
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Analytical Abstracts, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Food Science & Technology Abstracts, Veterinary Science Database
  • Anahtar Kelimeler: Deep eutectic solvents, Erythrosine, Food additives, Microextraction, Sample preparation, Spectrophotometry, Statistical analysis
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

In this study, a new microextraction procedure was developed for the extraction of trace amounts of Erythrosine from food, cosmetic and pharmaceutical samples before its determination by ultraviolet-visible spectrophotometry. The developed procedure is deep eutectic solvent-based sonication-assisted liquid-liquid microextraction (DES-SA-LLME) and has the characteristics of being green, simple and inexpensive. In the developed method, 5 different deep eutectic solvents (DES) were prepared and tested for the selective and efficient extraction of Erythrosine. DES-1, obtained by mixing 1,2-propanediol and choline chloride in a 1:2 molar ratio, respectively, was selected as the suitable DES. For simple and rapid optimization of experimental parameters (pH, DES-1 vol, temperature and sonication time), central composite design (CCD) based on surface response methodology was used. When the analytical parameters of the method were investigated, the working range was calculated as 1–400 ng mL−1, enrichment factor (EF) was 175, detection limit (LOD) was 1.0 ng mL−1 and relative standard deviation (RSD) was 2.2 %. The DES-SA-LLME procedure provided very satisfying thruputs for the separation and determination of Erythrosine from complex sample matrices. Within the scope of the study, the recoveries achieved were in the range of 94.8–102.7 %