Lung Volume and Density Assessment in Crimean–Congo Hemorrhagic Fever Patients: Correlations With SGS

BAŞPINAR N., BÜYÜKTUNA S. A.

Journal of Tropical Medicine, cilt.2026, sa.1, 2026 (SCI-Expanded, Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 2026 Sayı: 1
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1155/jotm/6848103
  • Dergi Adı: Journal of Tropical Medicine
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, Directory of Open Access Journals
  • Anahtar Kelimeler: Crimean, hemorrhagic fever, lung, multidetector computed tomography
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Crimean–Congo hemorrhagic fever (CCHF) is a viral disease that can cause multiorgan failure and death, yet its pulmonary involvement remains poorly understood. This retrospective study included 107 patients diagnosed with CCHF and evaluated the relationship between lung volume and density changes on computed tomography (CT) and the Severity Grading Score (SGS). Lung volume, mean density, and the percentage of high-attenuation areas (HAA%) were measured on noncontrast chest CT scans and compared with SGS risk groups (mild, moderate, and severe). Significant differences were observed in lung volume and density between the mild–moderate and mild–severe groups, but not between the moderate–severe groups. For the left lung, HAA% differed significantly between both mild–severe and moderate–severe groups. A significant correlation between SGS and CT-based lung parameters suggests that quantitative lung imaging may aid in risk stratification and clinical management of CCHF.