Objective: Fibromyalgia syndrome (FMS) is a chronic widespread painful syndrome of middle-aged women. Psychological problems, especially depression and anxiety are common among the FMS patients. High alexithymia scores have been reported before. It is suggested that FMS has a negative effect on family and marital relationships. In this study, we aimed to search whether there is a difference between the FMS and osteoarthritis patients with chronic pain regarding the psychopathologic features, alexithymia and the effects of these diseases on family and marital relationships.