In Vitro Antioxidant Evaluation of Some Mannich Bases which Contain Bis-1,2,4-Triazole Derivative


PARLAK A. E. , KARATEPE M., KOPARIR M., DURNA DAŞTAN S. , Alayunt N. O. , ULAŞ M., ...More

JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN, vol.37, no.6, pp.1192-1204, 2015 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 6
  • Publication Date: 2015
  • Title of Journal : JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN
  • Page Numbers: pp.1192-1204

Abstract

This study aims to examine the antioxidant effects of some Mannich bases containing bis-1, 2, 4 triazole, which are synthesized afresh. The antioxidant activities of the derivatives were measured using different methods in this study, including reducing power capacity, metal chelating activity, superoxide anion radicals scavenging activity, H2O2 scavenging activity and hydroxyl radical scavenging. As a result, derivatives had efficient antioxidant and free radical scavenging activity when compared to ascorbic acid, BHT and alpha-tocopherol as associated antioxidants.