In Vitro Antioxidant Evaluation of Some Mannich Bases which Contain Bis-1,2,4-Triazole Derivative

PARLAK A. E., KARATEPE M., KOPARIR M., DURNA DAŞTAN S., Alayunt N. O., ULAŞ M., ...Daha Fazla

JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN, cilt.37, sa.6, ss.1192-1204, 2015 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 6
  • Basım Tarihi: 2015
  • Dergi Adı: JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1192-1204
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

This study aims to examine the antioxidant effects of some Mannich bases containing bis-1, 2, 4 triazole, which are synthesized afresh. The antioxidant activities of the derivatives were measured using different methods in this study, including reducing power capacity, metal chelating activity, superoxide anion radicals scavenging activity, H2O2 scavenging activity and hydroxyl radical scavenging. As a result, derivatives had efficient antioxidant and free radical scavenging activity when compared to ascorbic acid, BHT and alpha-tocopherol as associated antioxidants.