Serum NOX-2 concentrations and paraoxanase-1 activity in subclinical hypothyroidism: a pilot study


DUMAN G. , Dugan H. O.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.45, ss.271-276, 2020 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 45 Konu: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1515/tjb-2018-0159
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Sayfa Sayıları: ss.271-276

Özet

Objective: Subclinical hypothyroidism (SH) is one of the most prevalent endocrine disorders. Although recent data suggest an imbalanced oxidative status in SH, the mechanisms of increased oxidative stress are poorly figured out. The primary goal of this research was to analyze potential sources of ROS and the relationship between serum NOX-2 levels and paraoxonase-1 (PON-1) activity in SH. Serum lipid changes in SH patients which had been determined were compared to healthy control group.