Post-collisional granitoid plutons intrude obducted Neo-Tethyan ophiolitic rocks in central and eastern Central Anatolia. The Bizmisen and Calti plutons and the ophiolitic rocks that they intrude are overlain by fossiliferous and flyschoidal sedimentary rocks of the early Miocene Kemah Formation. These sedimentary rocks were deposited in basins that developed at the same time as tectonic unroofing of the plutons along E-W and NW-SE trending faults in Oligo-Miocene time. Mineral separates from the Bizmisen and Calti plutons yield K-Ar ages ranging from 42 to 46 Ma, and from 40 to 49 Ma, respectively. Major, trace, and rare-earth element geochemistry as well as mineralogical and textural evidence reveals that the Bizmisen pluton crystallized first, followed at shallower depth by the Calti pluton from a medium-K calcalkaline, I-type hybrid magma which was generated by magma xing of coeval mafic and felsic magmas.