Lactic acidosis induced by metformin in a chronic hemodialysis patient with diabetes mellitus type 2

Altun E., KAYA B., PAYDAŞ S., Sariakcali B., KARAYAYLALI İ.

HEMODIALYSIS INTERNATIONAL, cilt.18, sa.2, ss.529-531, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1111/hdi.12109
  • Dergi Adı: HEMODIALYSIS INTERNATIONAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.529-531
  • Sivas Cumhuriyet Üniversitesi Adresli: Hayır

Özet

Metformin is a biguanide group oral antidiabetic drug used for the treatment of type 2 diabetes mellitus. Nausea, vomiting, diarrhea, abdominal pain, and anorexia are the most common adverse effects encountered during treatment. Lactic acidosis is a serious side effect seen with metformin use, and while the incidence of lactic acidosis is similar to other oral antidiabetics, metformin is not recommended to patients with certain risk factors, such as cardiovascular, pulmonary, and renal and liver failure. We describe a chronic hemodialysis patient treated with metformin, presenting to the nephrology department with altered mental status.