Adsorption of bovine serum albumin onto radiation-crosslinked poly(acrylamide/acrylic acid)

Creative Commons License

Oztop H. N. , Saraydin D. , Solpan D., Guven O.

ADSORPTION SCIENCE & TECHNOLOGY, vol.22, no.4, pp.311-325, 2004 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 4
  • Publication Date: 2004
  • Doi Number: 10.1260/0263617041514929
  • Page Numbers: pp.311-325


Poly(acrylamide/acrylic acid) (AAm/AAc) hydrogels were prepared at initial acrylic acid compositions of 70, 80 and 85 mol%, respectively. Mixtures of AAm and AAc monomers were irradiated in a Co-60 gamma-ray source at a dosage of 8 kGy. These hydrogels were used in experiments associated with the swelling, diffusion and adsorption of bovine serum albumin (BSA) from aqueous solution. The data obtained allowed the swelling and diffusion parameters for the hydrogels to be calculated. In the BSA adsorption experiments, the adsorption kinetics together with the influence of the pH of the medium, the initial BSA concentration and the composition of the hydrogels on the adsorption efficiency of the AAm/AAc hydrogels were all studied.