The fatigue, anxiety and depression of cancer patients (n = 80) who were admitted to an oncology hospital were investigated. Data were collected using a personal information form, the cancer fatigue scale and the hospital anxiety and depression scale. It was determined a positive significant correlations between fatigue, anxiety and depression levels of the patients (p < 0.05). It was determined that there was a negative significant relation between hemoglobin level and fatigue. The level of fatigue, anxiety and depression was higher in female patients. Patients who have another disease and indicated that the disease hinders the activities of daily living had a higher level of physical ad cognitive fatigue. Literate patients had high level of physical, emotional, cognitive fatigue and depression. The cancer patients experience fatigue, anxiety and depression. Convenient attempts should be planned in order to evaluate the case of fatigue, anxiety and depression comprehensively in treatment and care process of the cancer patients. (C) 2011 Elsevier GmbH. All rights reserved.