PREPARATION AND CHARACTERIZATION OF MOLECULAR IMPRINTED POLYMER FOR THE SELECTIVE RECOGNITION OF SEROTONIN


HEPOKUR C. , ÖZTOP H. N. , SARAYDIN D.

CHEMISTRY & CHEMICAL TECHNOLOGY, cilt.14, ss.195-204, 2020 (ESCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 14 Konu: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.23939/chcht14.02.195
  • Dergi Adı: CHEMISTRY & CHEMICAL TECHNOLOGY
  • Sayfa Sayıları: ss.195-204

Özet

Molecularly imprinted polymers (MIPs) were prepared for highly selective recognition of serotonin. Acrylamide, methacrylic acid and methacrylamide were selected as the monomers for the production of MIPs. Functional monomers were polymerized with ethylene glycol dimethacrylate, 1,4-butanediol diacrylate, and trimethylpropane triacrylate with serotonin (MIP-EGDMA, MIP-BUT and MIP-TMT). Serotonin was removed from MIP by the mixture of methanol/acetic acid (4:1). Nonimprinted polymers (NIPs) were synthesized without serotonin (NIP-EGDMA, NIP-BUT and NIP-TMT). For the characterization of synthesized polymers FTIR, DSC, TGA, and SEM analysis were investigated. The parameters that affect the adsorption of serotonin on polymers such as temperature, pH and concentration were evaluated. The selectivity and reusability studies were also investigated.