Association between single nucleotide polymorphisms in prospective genes and susceptibility to ankylosing spondylitis and inflammatory bowel disease in a single centre in Turkey


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Kucuksahin O., ATEŞ A., Turkcapar N., TÖRÜNER M., Turgay M., Duman T., ...More

TURKISH JOURNAL OF GASTROENTEROLOGY, vol.27, no.4, pp.317-324, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 4
  • Publication Date: 2016
  • Doi Number: 10.5152/tjg.2016.15466
  • Title of Journal : TURKISH JOURNAL OF GASTROENTEROLOGY
  • Page Numbers: pp.317-324
  • Keywords: Ankylosing spondylitis, inflammatory bowel disease, single nucleotide polymorphism, GENOME-WIDE ASSOCIATION, CROHNS-DISEASE, NONSYNONYMOUS SNPS, ERAP1, LOCI, POPULATION, GENETICS, HLA-B27, SPONDYLOARTHROPATHIES, PATHOGENESIS

Abstract

Background/Aims: To establish the prevalence of the single nucleotide polymorphisms (SNPs) of endoplasmic reticulum aminopeptidase 1 (ERAP1), IL-23 receptor (IL-23R), signal transducer and activator of transcription 3 (STAT-3) and Janus kinase 2 (JAK-2) in ankylosing spondylitis (AS) and inflammatory bowel disease (IBD) in a Turkish population.