Effect of L-NAME on decreased ileal muscle contractility induced by peritonitis in rats


Koyluoglu G., Kaya T., Bagcivan I., Yildiz T.

JOURNAL OF PEDIATRIC SURGERY, vol.37, no.6, pp.901-905, 2002 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 6
  • Publication Date: 2002
  • Doi Number: 10.1053/jpsu.2002.32907
  • Title of Journal : JOURNAL OF PEDIATRIC SURGERY
  • Page Numbers: pp.901-905

Abstract

Background/Purpose: It is now well established that intestinal inflammation is associated with disturbed contractility. The aim of this study was to determine the effects of peritonitis on longitudinal ileum smooth muscle responses to KCl, carbachol and substance P (SP) and to examine the role of nitric oxide (NO) and N-omega-nitro-L-arginine methylester (L-NAME) on ileal contractility in this peritonitis model.