Effect of L-NAME on decreased ileal muscle contractility induced by peritonitis in rats


Koyluoglu G., Kaya T., Bagcivan I., Yildiz T.

JOURNAL OF PEDIATRIC SURGERY, cilt.37, ss.901-905, 2002 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 37 Konu: 6
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1053/jpsu.2002.32907
  • Dergi Adı: JOURNAL OF PEDIATRIC SURGERY
  • Sayfa Sayıları: ss.901-905

Özet

Background/Purpose: It is now well established that intestinal inflammation is associated with disturbed contractility. The aim of this study was to determine the effects of peritonitis on longitudinal ileum smooth muscle responses to KCl, carbachol and substance P (SP) and to examine the role of nitric oxide (NO) and N-omega-nitro-L-arginine methylester (L-NAME) on ileal contractility in this peritonitis model.