An FPSE-HPLC-PDA method for rapid determination of solar UV filters in human whole blood, plasma and urine


Locatelli M., Furton K. G., Tartaglia A., Sperandio E., Ulusoy H. İ., Kabir A.

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, ss.40-50, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası:
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.jchromb.2019.04.028
  • Dergi Adı: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.40-50
  • Anahtar Kelimeler: FPSE-HPLC-PDA, Method validation, Benzophenone-derivative UV filters, Whole blood, Plasma and urine, Human exposure, Clinical and diagnostic applications, ARRAY DETECTION METHOD, LIQUID-CHROMATOGRAPHY, MASS-SPECTROMETRY, ECOLOGICAL RISKS, BENZOPHENONE, PHASE, MICROEXTRACTION, ACID, 2-HYDROXY-4-METHOXYBENZOPHENONE, QUANTIFICATION
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

This paper reports a novel fabric phase sorptive extraction-high performance liquid chromatography-photodiode array detection (FPSE-HPLC-PDA) method for the simultaneous extraction and analysis of six benzophenone derivative UV filters including benzophenone (BZ); 5-benzoyl-4-hydroxy-methoxybenzenesulfonic acid (BP-4); bis(4-hydroxyphenyl)methanone (4-DHB); bis(2,4-dihydroxyphenyl)methanone (BP-2); (2,4-dihydroxybenzophenone) (BP-1) and 2,2'-dihydroxy-4-methoxybenzophenone (DHMB) in human whole blood, plasma and urine samples.