CARDIAC BIOMARKERS IN PREMATURE CALVES WITH RESPIRATORY DISTRESS SYNDROME


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AYDOĞDU U. , Yildiz R., Guzelbektes H., COŞKUN A. , ŞEN İ.

ACTA VETERINARIA HUNGARICA, cilt.64, ss.38-46, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 64 Konu: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1556/004.2016.004
  • Dergi Adı: ACTA VETERINARIA HUNGARICA
  • Sayfa Sayıları: ss.38-46

Özet

The aim of this study was to determine the clinical relevance of cardiac biomarkers [troponin I and T, creatine kinase-MB fraction (CK-MB) and lactate dehydrogenase (LDH)] in premature calves with respiratory distress syndrome. Seventy premature calves were admitted to the clinic within 24 h after birth. Respiratory distress syndrome was diagnosed in premature calves by clinical examination and venous blood gas analysis. Ten healthy calves, aged 5 days, were used as control. Cardiac troponin I and T were analysed using ELISA and ELFA, respectively. Serum CK-MB and LDH were also analysed in an automatic analyser. The calves had low venous pH, pO(2), O-2 saturation and high pCO(2) values consistent with dyspnoea, hypoxaemia, and inadequate oxygen delivery. Mean serum troponin I, troponin T, CK-MB and LDH levels were increased in the premature calves compared to the control group. In conclusion, the results in this study demonstrated that serum CK-MB, troponin I and troponin T concentrations could be used for evaluating myocardial injury in premature calves with respiratory distress syndrome.