Community-acquired CTX-M-15-type ESBL-producing Escherichia coli meningitis: a case report and literature review
JOURNAL OF INFECTION IN DEVELOPING COUNTRIES, cilt.7, sa.5, ss.424-431, 2013 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 7 Sayı: 5
- Basım Tarihi: 2013
- Doi Numarası: 10.3855/jidc.2820
- Dergi Adı: JOURNAL OF INFECTION IN DEVELOPING COUNTRIES
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.424-431
- Anahtar Kelimeler: Escherichia coli, CTX-M-15, meningitis, SPECTRUM-BETA-LACTAMASE, URINARY-TRACT-INFECTIONS, BACTERIAL-MENINGITIS, RISK-FACTORS, ENTEROBACTERIACEAE, TURKEY, EPIDEMIOLOGY, RESISTANCE, UNIVERSITY, MORTALITY
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sivas Cumhuriyet Üniversitesi Adresli: Evet
Özet
In this report, a case of community-acquired acute bacterial meningitis (CA-ABM) caused by CTX-M-15-producing Escherichia coli in an elderly male patient was presented in the light of literature. Cultures of cerebrospinal fluid, blood, ear discharge, and stool samples yielded CTX-M-15-producing E. coli in-vitro, which was resistant to the extended-spectrum cephalosporins and ciprofloxacin and susceptible to imipenem, meropenem and amikacin. Meningitis was treated with parenteral meropenem plus parenteral and intraventricular amikacin administration. Since bacterial meningitis is a life-threatening infection, empiric antibiotic therapy with carbapenem can be started before the culture results are obtained, mainly in areas where the ESBL epidemiology is well known.