Determination of chemical profile, antioxidant, DNA damage protection and antiamoebic activities of Teucrium polium and Stachys iberica

TEPE B., DEĞERLİ S., ARSLAN S., MALATYALI E., Sarikurkcu C.

FITOTERAPIA, cilt.82, sa.2, ss.237-246, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 82 Sayı: 2
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.fitote.2010.10.006
  • Dergi Adı: FITOTERAPIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.237-246
  • Anahtar Kelimeler: Teucrium polium, Stachys iberica, Antioxidant activity, DNA damage protection, Antiamoebic activity, IN-VITRO SUSCEPTIBILITY, ENTAMOEBA-HISTOLYTICA, LIPID-PEROXIDATION, MEDICINAL-PLANTS, ANTIPLASMODIAL ACTIVITIES, AROMATIC PLANTS, EXTRACTS, FLAVONOIDS, METRONIDAZOLE, CYTOTOXICITY
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

This work deals with the evaluation of in vitro antioxidant, DNA preventing and antiamoebic activities of the water extracts of Teucrium polium and Stachys iberica. In all systems, T. polium extract exhibited excellent activity potential than that of S. iberica. The amount of total phenolics and flavonoids were high in this extract. In the presence of 40 mg/ml T. polium extract, a significant protection was observed for native super coiled DNA of pBR322 plasmid DNA. In the presence of 32 mg/ml of T polium extract, no trophozoite was after the 24th hour. (C) 2010 Elsevier B.V. All rights reserved.